This is is an interactive chart. Mouseover points on the top line plots that summarize the per-site escape averaged across all sera and for individual sera. You can use the top zoom-bar or the line plots to zoom in on specific sites to show in the heatmaps that give per-mutation effects on serum escape or protein function. The options at the bottom let you only show escape for sites with some minimal functional effect (more deleterious mutations are grayed out in heatmap), choose the site summary metric, or floor the escape at zero.
Analysis by Bernadeta Dadonaite and Jesse Bloom (2023).
See https://github.com/dms-vep/SARS-CoV-2_XBB.1.5_spike_DMS for code/data.